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Spinal Tract Pathology in AIDS:Postmortem MRI Correlation with Neuropathology
Neuroradiology 37:134-138, , 1995
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Article Abstract
Vacuolar myelopathy(VM)and tract pallor are poorly understood spinal tract abnormalities in patients with the acquired immunodeficiency syndrome (AIDS).We studied the ability of magnetic resonance imaging(MRI)to detect these changes in spinal cord specimens postmortem and whether criteria could be formulated which would allow these conditions to be differentiated from other lesions of the spinal cord in AIDS,such as lymphoma,cytomegalovirus(CMV)and human immunodeficiency virus(HIV) myelitis.The findings in VM and tract pallor on proton density and T2 weighted MRI were increased signal from the affected white matter tracts, present on multiple contiguous slices and symmetrical in most cases.The pattern was sufficiently distinct to differentiate spinal tract pathology from other spinal cord lesions in AIDS.
 
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acquired immunodeficiency syndrome
acquired immunodeficiency syndrome myelopathy
human immunodeficiency virus type 1
MRI
MRI,abnormal
MRI,spinal cord
myelopathy
myelopathy,vacuolar
neuropathology
spinal cord
spinal cord,lesion of
spinal cord,pathologic exam of

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